More severe impairment of manual dexterity in bipolar disorder compared to unipolar major depression

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More severe impairment of manual dexterity in bipolar disorder compared to unipolar major depression.

BACKGROUND Mood disorders are associated with various neurocognitive deficits. However, few studies have reported the impairment of motor dexterity in unipolar depression and bipolar disorder. In the present study, manual dexterity was compared between unipolar major depression, bipolar disorder, and healthy controls. METHODS Manual dexterity was assessed by the Purdue pegboard test in 98 pat...

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Life-event specificity: bipolar disorder compared with unipolar depression.

BACKGROUND Little is known about the impact of different types of stressful events (for example divorce v. bereavement) on unipolar depression compared with bipolar disorder. Inconsistencies exist concerning the association between independent events (beyond an individual's control, such as bereavement) and bipolar disorder. AIMS To examine the role of specific, independent and dependent even...

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Bipolar Disorder and the TCI: Higher Self-Transcendence in Bipolar Disorder Compared to Major Depression

Personality traits are potential endophenotypes for genetic studies of psychiatric disorders. One personality theory which demonstrates strong heritability is Cloninger's psychobiological model measured using the temperament and character inventory (TCI). 277 individuals who completed the TCI questionnaire as part of the South Island Bipolar Study were also interviewed to assess for lifetime ps...

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Antidepressant-associated mood-switching and transition from unipolar major depression to bipolar disorder: a review.

OBJECTIVES Compare reported rates of mood-shifts from major depression to mania/hypomania/mixed-states during antidepressant (AD)-treatment and rates of diagnostic change from major depressive disorder (MDD) to bipolar disorder (BPD). METHODS Searching computerized literature databases, followed by summary analyses. RESULTS In 51 reports of patients diagnosed with MDD and treated with an AD...

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Conversion from unipolar depression to bipolar depression

BACKGROUND Clinicians, both psychiatrists and non-psychiatrists, underdiagnose bipolar disorder in a substantial proportion of depressed patients. Correct diagnosis is important since the prescription of antidepressants without mood stabilizers may precipitate a switch to mania. In patients presenting with depression, what are the odds they will turn out to really be bipolar? There are few long...

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ژورنال

عنوان ژورنال: Journal of Affective Disorders

سال: 2012

ISSN: 0165-0327

DOI: 10.1016/j.jad.2011.11.031